Impact of prolonged mechanical ventilation on diaphragmatic protein synthesis
نویسندگان
چکیده
منابع مشابه
Impact of prolonged assisted ventilation on diaphragmatic efficiency: NAVA versus PSV
BACKGROUND Prolonged controlled mechanical ventilation depresses diaphragmatic efficiency. Assisted modes of ventilation should improve it. We assessed the impact of pressure support ventilation versus neurally adjusted ventilator assist on diaphragmatic efficiency. METHOD Patients previously ventilated with controlled mechanical ventilation for 72 hours or more were randomized to be ventilat...
متن کامل[Prolonged mechanical ventilation probability model].
OBJECTIVE To design a probability model for prolonged mechanical ventilation (PMV) using variables obtained during the first 24 hours of the start of MV. DESIGN An observational, prospective, multicenter cohort study. SCOPE Thirteen Spanish medical-surgical intensive care units. PATIENTS Adult patients requiring mechanical ventilation for more than 24 hours. INTERVENTIONS None. STUDY ...
متن کاملDiaphragmatic contraction during assisted mechanical ventilation.
Indirect evidence from airway pressure recordings in mechanically ventilated patients suggests that the diaphragm exhibits contractile activity beyond that required to trigger a ventilator-assisted breath. We used the diaphragmatic EMG to provide direct evidence of persistent contractile activity and studied the effects of alterations in ventilator-delivered flow rate and tidal volume on the du...
متن کاملDiaphragmatic strength during weaning from mechanical ventilation.
Respiratory muscle weakness is considered to be a factor in the inability to wean from mechanical ventilation. To assess this possibility, the present study examined the mechanical behavior of the diaphragm by measuring the change in transdiaphragmatic pressure (delta Pdi) during weaning. Nine "T-piece" weanings were carried out in seven patients with prior weaning failure and were terminated w...
متن کاملImpact of sepsis on the dynamics of diaphragmatic function in patients under mechanical ventilation
Methods We prospectively included mechanically ventilated patients of a 16-beds medical intensive care unit. Diaphragmatic function was estimated by the gold standard method using bilateral anterior magnetic stimulation (Ptr,stim) at two distinct time points: 1) during the first 24 hours of mechanical ventilation and 2) in the 24 hours after switching to spontaneous ventilation mode. Sepsis was...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2013
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.27.1_supplement.lb784